Smooth Lines. Correct Scars. Stimulate Collagen That Lasts. Bellafill is the only FDA-approved dermal filler that stimulates your body’s own collagen for results lasting up to five years — so
you can stop the cycle of repeat injections. 

What is Bellafill?

If you’ve been getting dermal fillers every six to twelve months to keep smile lines at bay, you already know the routine: schedule the appointment, take the time, pay the cost, and do it all again a few months later.

Over time, many patients experience what’s known as “filler fatigue” — the frustration of maintaining results that were never designed to last. A recent Harris Poll survey found that out of nine million dermal filler patients in the U.S., nearly eight million are affected by this cycle.

Bellafill offers a fundamentally different approach. Rather than relying solely on a gel that the body absorbs over time, Bellafill combines two proven components to create results that are both immediate and long-lasting. A smooth collagen gel — making up about 80% of the product — provides instant volume and correction the moment it’s injected.

Suspended within that gel are tiny polymethyl methacrylate (PMMA) microspheres, a biocompatible acrylic material that has been used safely in medicine for more than 65 years. These microspheres form a stable scaffold deep within the skin, and over the following months, your body deposits its own natural collagen around them.

The result is a gradual transition: as the original collagen gel is naturally absorbed, your own collagen takes its place — maintaining smooth, natural-looking correction without repeated office visits. In the longest and largest prospective study ever conducted on a dermal filler, Bellafill was proven effective through five full years.

What Does Bellafill Treat?

Bellafill is FDA approved to treat two distinct concerns:

Nasolabial Folds (Smile Lines)

These are the creases that run from the sides of the nose to the corners of the mouth. They deepen naturally with age as facial volume diminishes and skin loses elasticity. Bellafill fills the fold immediately while stimulating lasting collagen support beneath the surface — with results proven to hold through five years in clinical studies.

Moderate to Severe Acne Scars

Bellafill is also the only FDA-approved injectable treatment for moderate to severe atrophic (depressed) acne scars on the cheeks in patients 21 and older. By filling the scar from beneath and encouraging new collagen growth, Bellafill elevates the depressed skin to match the surrounding surface — restoring a smoother, more even texture.

During your consultation, Dr. Gladstone will assess your areas of concern and determine whether Bellafill — alone or as part of a broader treatment plan — is the best approach for your goals.

What to Expect

What An injectable filler composed of smooth collagen gel and PMMA microspheres, designed to provide immediate correction and stimulate your body’s own long-term collagen production.

Where Nasolabial folds (smile lines) and moderate to severe atrophic acne scars on the cheeks.

Before Treatment A simple skin test is required prior to your first Bellafill treatment to confirm you are not sensitive to the bovine collagen component. This is typically performed at a preliminary visit, with treatment scheduled after a negative result.

Downtime Minimal — most patients return to normal activities immediately. Temporary swelling, redness, bruising, or tenderness at the injection site typically resolves within one to seven days.

Results Immediate volume and smoothing at the time of injection, with continued collagen development over the following months.

How Long Up to 5 years for nasolabial folds; up to 12 months for acne scars — among the longest-lasting results of any dermal filler available.

Unlike fillers that require touch-ups every few months, Bellafill’s collagen-stimulating mechanism means fewer appointments, less cumulative cost, and results that improve as your own collagen builds over time. It is the most-studied dermal filler on the market, backed by over one million syringes distributed and 17 years of post-market safety surveillance.

Results

Is Bellafill Right for You?

Bellafill is ideal for women and men, 21 and older, who are bothered by smile lines or acne scarring and want a lasting solution — not another temporary fix. It is especially well-suited for patients who have been maintaining results with hyaluronic acid fillers and are ready for something that won’t require the same ongoing commitment.

Bellafill is safe for all skin types and colors. However, patients with a history of severe allergies, a known allergy to bovine collagen or lidocaine, a bleeding disorder, or a tendency toward thick or excessive scar formation should discuss these factors with their doctor before treatment.

During your complimentary consultation, Dr. Gladstone will evaluate your facial structure and skin concerns and discuss whether Bellafill — alone or in combination with other treatments — is the right approach for your goals.

The Gladstone Clinic is passionately committed to reflecting your inner beauty. Using the latest and most advanced procedures for cosmetic and reconstructive surgery, our team offers services emphasizing overall health and wellness to the residents of Blackhawk, San Ramon, Danville, Pleasanton, San Francisco, and the surrounding communities in California. Please contact us today to schedule a complimentary consultation!

*Individual results may vary.

FAQs

Results for nasolabial folds have been proven effective through 5 years. For acne scars, results have been established through 12 months.

Bellafill provides immediate volume with its collagen gel. Over time, the PMMA microspheres remain as a scaffold, encouraging your body to produce its own natural collagen for long-term smoothness.

Yes. Bellafill has been proven safe in the largest and longest prospective dermal filler study ever completed, with over 1 million syringes distributed and only a 0.11% adverse event rate over 17 years.

You can return to your normal activities right away. Some temporary swelling, redness, or bruising at the treatment site typically resolves within 1-7 days.

Women and men age 21 and older who are bothered by smile lines or moderate to severe acne scars. A skin test is required before your first treatment to confirm you’re not sensitive to the product.

The cost varies depending on the number of syringes needed. During your consultation at Gladstone Clinic, we’ll create a personalized treatment plan that fits your goals and budget.